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Age-dependent vulnerability to endotoxemia is associated with reduction of anticoagulant factors activated protein C and thrombomodulin

The protein C (PC) pathway is an important anticoagulant mechanism that prevents thrombosis during the systemic inflammatory response. Thrombomodulin (TM), an endothelial cell membrane receptor, accelerates the conversion of PC to activated protein C (APC), which leads to the down-regulation of thro...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Starr, Marlene E., Ueda, Junji, Takahashi, Hitoshi, Weiler, Hartmut, Esmon, Charles T., Evers, B. Mark, Saito, Hiroshi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890181/
https://ncbi.nlm.nih.gov/pubmed/20348393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-246678
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