Increased coagulation and suppressed generation of activated protein C in aged mice during intra-abdominal sepsis

Sepsis is a life-threatening clinical condition that is particularly serious among the elderly who experience considerably higher mortality rates compared with younger patients. Using a sterile endotoxemia model, we previously reported age-dependent mortality in conjunction with enhanced coagulation...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Starr, Marlene E., Takahashi, Hitoshi, Okamura, Daiki, Zwischenberger, Brittany A., Mrazek, Amy A., Ueda, Junji, Stromberg, Arnold J., Evers, B. Mark, Esmon, Charles T., Saito, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338937/
https://ncbi.nlm.nih.gov/pubmed/25380813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00289.2014
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