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Effects of membrane and soluble EPCR on the hemostatic balance and endotoxemia in mice

Recent studies have shown that endothelial protein C receptor (EPCR) polymorphisms and soluble EPCR levels are associated with thrombotic diseases. It is unknown whether membrane EPCR (mEPCR) heterozygosity and/or physiologically elevated sEPCR levels directly impact the hemostatic balance and the o...

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Detalhes bibliográficos
Main Authors: Zheng, Xunzhen, Li, Weihong, Gu, Jian-Ming, Qu, Dongfeng, Ferrell, Gary L., Esmon, Naomi L., Esmon, Charles T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1785131/
https://ncbi.nlm.nih.gov/pubmed/17023579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-06-032086
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