Loading...
The importance of vicinal cysteines, C1669 and C1670, for von Willebrand factor A2 domain function
The von Willebrand factor (VWF) A2 crystal structure has revealed the presence of a rare vicinal disulfide bond between C1669 and C1670, predicted to influence domain unfolding required for proteolysis by ADAMTS13. We prepared VWF A2 domain fragments with (A2-VicCC, residues 1473-1670) and without t...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2010
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890177/ https://ncbi.nlm.nih.gov/pubmed/20354169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-12-257949 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|