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Innate-Like Control of Human iNKT Cell Autoreactivity via the Hypervariable CDR3β Loop
Invariant Natural Killer T cells (iNKT) are a versatile lymphocyte subset with important roles in both host defense and immunological tolerance. They express a highly conserved TCR which mediates recognition of the non-polymorphic, lipid-binding molecule CD1d. The structure of human iNKT TCRs is uni...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2889927/ https://ncbi.nlm.nih.gov/pubmed/20585371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000402 |
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