Effects of Localized Neurotrophin Gene Expression on Spiral Ganglion Neuron Resprouting in the Deafened Cochlea

A cochlear implant may be used to electrically stimulate spiral ganglion neurons (SGNs) in people with severe sensorineural hearing loss (SNHL). However, these neurons progressively degenerate after SNHL due to loss of neurotrophins normally supplied by sensory hair cells (HCs). Experimentally, exog...

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Main Authors: Wise, Andrew K, Hume, Clifford R, Flynn, Brianna O, Jeelall, Yogesh S, Suhr, Courtney L, Sgro, Beatrice E, O'Leary, Stephen J, Shepherd, Robert K, Richardson, Rachael T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889745/
https://ncbi.nlm.nih.gov/pubmed/20216530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.28
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