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Chronic Neurotrophin Delivery Promotes Ectopic Neurite Growth From the Spiral Ganglion of Deafened Cochleae Without Compromising the Spatial Selectivity of Cochlear Implants

Cochlear implants restore hearing cues in the severe– profoundly deaf by electrically stimulating spiral ganglion neurons (SGNs). However, SGNs degenerate following loss of cochlear hair cells, due at least in part to a reduction in the endogenous neurotrophin (NT) supply, normally provided by hair...

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Publicado en:J Comp Neurol
Autores principales: Landry, Thomas G., Fallon, James B., Wise, Andrew K., Shepherd, Robert K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4555354/
https://ncbi.nlm.nih.gov/pubmed/23436344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.23318
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