Improved Auditory Nerve Survival with Nanoengineered Supraparticles for Neurotrophin Delivery into the Deafened Cochlea

Cochlear implants electrically stimulate spiral ganglion neurons (SGNs) in order to provide speech cues to severe-profoundly deaf patients. In normal hearing cochleae the SGNs depend on endogenous neurotrophins secreted by sensory cells in the organ of Corti for survival. SGNs gradually degenerate f...

Full description

Saved in:
Bibliographic Details
Published in:PLoS One
Main Authors: Wise, Andrew K., Tan, Justin, Wang, Yajun, Caruso, Frank, Shepherd, Robert K.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082918/
https://ncbi.nlm.nih.gov/pubmed/27788219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164867
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items