The effect of deafness duration on neurotrophin gene therapy for spiral ganglion neuron protection

A cochlear implant can restore hearing function by electrically exciting spiral ganglion neurons (SGNs) in the deaf cochlea. However, following deafness SGNs undergo progressive degeneration ultimately leading to their death. One significant cause of SGN degeneration is the loss of neurotrophic supp...

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Main Authors: Wise, Andrew K., Tu, Tian, Atkinson, Patrick J., Flynn, Brianna O., Sgro, Beatrice E., Hume, Cliff, O'Leary, Stephen J., Shepherd, Robert K., Richardson, Rachael T.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152700/
https://ncbi.nlm.nih.gov/pubmed/21557994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2011.04.010
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