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Neuronal death during combined intermittent hypoxia/hypercapnia is due to mitochondrial dysfunction

Breathing-disordered states, such as in obstructive sleep apnea, which are cyclical in nature, have been postulated to induce neurocognitive morbidity in both pediatric and adult populations. The oscillatory nature of intermittent hypoxia, especially when chronic, may mimic the paradigm of ischemia-...

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Bibliografske podrobnosti
Main Authors: Douglas, Robert M., Ryu, Julie, Kanaan, Amjad, del Carmen Rivero, Maria, Dugan, Laura L., Haddad, Gabriel G., Ali, Sameh S.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2010
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889641/
https://ncbi.nlm.nih.gov/pubmed/20357179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00298.2009
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