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Neuronal death during combined intermittent hypoxia/hypercapnia is due to mitochondrial dysfunction

Breathing-disordered states, such as in obstructive sleep apnea, which are cyclical in nature, have been postulated to induce neurocognitive morbidity in both pediatric and adult populations. The oscillatory nature of intermittent hypoxia, especially when chronic, may mimic the paradigm of ischemia-...

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Detalhes bibliográficos
Main Authors: Douglas, Robert M., Ryu, Julie, Kanaan, Amjad, del Carmen Rivero, Maria, Dugan, Laura L., Haddad, Gabriel G., Ali, Sameh S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889641/
https://ncbi.nlm.nih.gov/pubmed/20357179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00298.2009
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