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Dynamics and processes of copy number instability in human γ-globin genes
Copy number variation in the human genome is prevalent but relatively little is known about the dynamics of DNA rearrangement. We therefore used the duplicated γ-globin genes as a simple system to explore de novo copy number changes. Rearrangements that changed gene number were seen in both germline...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2889564/ https://ncbi.nlm.nih.gov/pubmed/20404158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003634107 |
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