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Processes of de novo duplication of human α-globin genes

Ectopic recombination between repeated but nonallelic DNA sequences plays a major role in genome evolution, creating gene families and generating copy number variation and pathological rearrangements in human chromosomes. Previous studies on the α2- and α1-globin genes have shown that de novo deleti...

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Detalhes bibliográficos
Main Authors: Lam, Kwan-Wood G., Jeffreys, Alec J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1904127/
https://ncbi.nlm.nih.gov/pubmed/17573529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703856104
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