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Processes of copy-number change in human DNA: The dynamics of α-globin gene deletion
Ectopic recombination between locally repeated DNA sequences is of fundamental importance in the evolution of gene families, generating copy-number variation in human DNA and often leading to pathological rearrangements. Despite its importance, little is known about the dynamics and processes of the...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1482541/ https://ncbi.nlm.nih.gov/pubmed/16709669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602690103 |
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