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Mapping the physical and functional interactions between the tumor suppressors p53 and BRCA2
p53 maintains genome integrity either by regulating the transcription of genes involved in cell cycle, apoptosis, and DNA repair or by interacting with partner proteins. Here we provide evidence for a direct physical interaction between the tumor suppressors p53 and BRCA2. We found that the transact...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2889359/ https://ncbi.nlm.nih.gov/pubmed/20421506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003689107 |
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