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A Promising Therapeutic Approach for Treatment of Posterior Uveitis: Recombinant T Cell Receptor Ligand Protects Lewis Rats from Acute and Recurrent Experimental Autoimmune Uveitis

INTRODUCTION: Chronic autoimmune uveitis is a major cause of vision loss from intraocular inflammation in humans. In this study we report that a recombinant TCR ligand (RTL220) composed of the α1 and β1 domains of MHC class II molecules linked to the uveitogenic interphotoreceptor retinoid-binding p...

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Detalhes bibliográficos
Main Authors: Adamus, Grazyna, Karren, Landon J., Mooney, Jeff, Burrows, Gregory G.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889253/
https://ncbi.nlm.nih.gov/pubmed/20145422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000281815
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