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Neuroprotective Effects of Recombinant T-cell Receptor Ligand in Autoimmune Optic Neuritis in HLA-DR2 Mice

PURPOSE. Optic neuritis (ON) is a condition involving primary inflammation, demyelination, and axonal injury in the optic nerve and leads to apoptotic retinal ganglion cell (RGC) death, which contributes to the persistence of visual loss. Currently, ON has no effective treatment. The goal was to det...

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Detalhes bibliográficos
Main Authors: Adamus, Grazyna, Brown, Lori, Andrew, Shayne, Meza-Romero, Roberto, Burrows, Gregory G., Vandenbark, Arthur A.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292374/
https://ncbi.nlm.nih.gov/pubmed/22167100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8419
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