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HLA-DRα1 Constructs Block CD74 Expression and MIF Effects in Experimental Autoimmune Encephalomyelitis

CD74, the cell surface form of the MHC class II invariant chain, is a key inflammatory factor that is involved in various immune mediated diseases as part of the Macrophage Migration Inhibitory Factor (MIF) binding complex. However, little is known about the natural regulators of CD74 in this contex...

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Detalhes bibliográficos
Main Authors: Meza-Romero, Roberto, Benedek, Gil, Yu, Xiaolin, Mooney, Jeffery L., Dahan, Rony, Duvshani, Nerri, Bucala, Richard, Offner, Halina, Reiter, Yoram, Burrows, Gregory G., Vandenbark, Arthur A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028955/
https://ncbi.nlm.nih.gov/pubmed/24683185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303118
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