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Systemic Immunomodulation of Autoimmune Disease Using MHC-Derived Recombinant TCR Ligands
Human autoimmune disease involves local activation of antigen-specific CD4(+) T cells that produce inflammatory Th1 cytokines leading to the further recruitment and activation of lymphocytes and monocytes, resulting ultimately in the destruction of target tissue. Antigen presenting cells (APCs) init...
Bewaard in:
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2005
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3457802/ https://ncbi.nlm.nih.gov/pubmed/15853741 |
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