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Systemic Immunomodulation of Autoimmune Disease Using MHC-Derived Recombinant TCR Ligands

Human autoimmune disease involves local activation of antigen-specific CD4(+) T cells that produce inflammatory Th1 cytokines leading to the further recruitment and activation of lymphocytes and monocytes, resulting ultimately in the destruction of target tissue. Antigen presenting cells (APCs) init...

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Bibliografische gegevens
Hoofdauteur: Burrows, Gregory G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2005
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457802/
https://ncbi.nlm.nih.gov/pubmed/15853741
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