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Effective Arrestin–Specific Immunotherapy of Experimental Autoimmune Uveitis with RTL: A Prospect for Treatment of Human Uveitis

PURPOSE: To evaluate the immunotherapeutic efficacy of recombinant T cell receptor ligands (RTLs) specific for arrestin immunity in treatment of experimental autoimmune uveitis (EAU) in humanized leukocyte antigen (HLA-DR3) transgenic (Tg) mice. METHODS: We generated de novo recombinant human DR3-de...

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Detalhes bibliográficos
Main Authors: Kyger, Madison, Worley, Aneta, Huan, Jianya, McDowell, Hugh, Smith, W. Clay, Burrows, Gregory G., Mattapallil, Mary J., Caspi, Rachel R., Adamus, Grazyna
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763891/
https://ncbi.nlm.nih.gov/pubmed/24049712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.2.2.1
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