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Ohnologs in the human genome are dosage balanced and frequently associated with disease

About 30% of protein-coding genes in the human genome are related through two whole genome duplication (WGD) events. Although WGD is often credited with great evolutionary importance, the processes governing the retention of these genes and their biological significance remain unclear. One increasin...

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Detaylı Bibliyografya
Asıl Yazarlar: Makino, Takashi, McLysaght, Aoife
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889102/
https://ncbi.nlm.nih.gov/pubmed/20439718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914697107
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