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Dosage-sensitive genes in evolution and disease
For a subset of genes in our genome a change in gene dosage, by duplication or deletion, causes a phenotypic effect. These dosage-sensitive genes may confer an advantage upon copy number change, but more typically they are associated with disease, including heart disease, cancers and neuropsychiatri...
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| Publicado en: | BMC Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5580218/ https://ncbi.nlm.nih.gov/pubmed/28863777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-017-0418-y |
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