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The Role of Mitochondrial DNA Copy Number in Mammalian Fertility
Mammalian mitochondrial DNA (mtDNA) is a small, maternally inherited genome that codes for 13 essential proteins in the respiratory chain. Mature oocytes contain more than 150 000 copies of mtDNA, at least an order of magnitude greater than the number in most somatic cells, but sperm contain only ap...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Society for the Study of Reproduction, Inc.
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2888963/ https://ncbi.nlm.nih.gov/pubmed/20130269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.109.080887 |
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