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The Role of Mitochondrial DNA Copy Number in Mammalian Fertility
Mammalian mitochondrial DNA (mtDNA) is a small, maternally inherited genome that codes for 13 essential proteins in the respiratory chain. Mature oocytes contain more than 150 000 copies of mtDNA, at least an order of magnitude greater than the number in most somatic cells, but sperm contain only ap...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Society for the Study of Reproduction, Inc.
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2888963/ https://ncbi.nlm.nih.gov/pubmed/20130269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.109.080887 |
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