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Evaluation of mitochondrial DNA copy number estimation techniques

Mitochondrial DNA copy number (mtDNA-CN), a measure of the number of mitochondrial genomes per cell, is a minimally invasive proxy measure for mitochondrial function and has been associated with several aging-related diseases. Although quantitative real-time PCR (qPCR) is the current gold standard m...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Longchamps, Ryan J., Castellani, Christina A., Yang, Stephanie Y., Newcomb, Charles E., Sumpter, Jason A., Lane, John, Grove, Megan L., Guallar, Eliseo, Pankratz, Nathan, Taylor, Kent D., Rotter, Jerome I., Boerwinkle, Eric, Arking, Dan E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994099/
https://ncbi.nlm.nih.gov/pubmed/32004343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228166
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