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Evaluation of mitochondrial DNA copy number estimation techniques

Mitochondrial DNA copy number (mtDNA-CN), a measure of the number of mitochondrial genomes per cell, is a minimally invasive proxy measure for mitochondrial function and has been associated with several aging-related diseases. Although quantitative real-time PCR (qPCR) is the current gold standard m...

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Foilsithe in:PLoS One
Main Authors: Longchamps, Ryan J., Castellani, Christina A., Yang, Stephanie Y., Newcomb, Charles E., Sumpter, Jason A., Lane, John, Grove, Megan L., Guallar, Eliseo, Pankratz, Nathan, Taylor, Kent D., Rotter, Jerome I., Boerwinkle, Eric, Arking, Dan E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994099/
https://ncbi.nlm.nih.gov/pubmed/32004343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228166
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