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Number matters: control of mammalian mitochondrial DNA copy number

Regulation of mitochondrial biogenesis is essential for proper cellular functioning. Mitochondrial DNA (mtDNA) depletion and the resulting mitochondrial malfunction have been implicated in cancer, neurodegeneration, diabetes, aging, and many other human diseases. Although it is known that the dynami...

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Detalhes bibliográficos
Publicado no:J Genet Genomics
Main Authors: Clay Montier, Laura L., Deng, Janice, Bai, Yidong
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706993/
https://ncbi.nlm.nih.gov/pubmed/19302968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1673-8527(08)60099-5
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