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In vivo antitumor effect of a novel inhibitor of protein geranylgeranyltransferase I
Protein geranylgeranyltransferase-I catalyzes protein geranylgeranylation which is critical for the function of proteins such as Rho, Rac and Ral. We previously identified several small molecule inhibitors of GGTase-I from an allenoate-derived compound library and showed that these compounds exhibit...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2888841/ https://ncbi.nlm.nih.gov/pubmed/19417142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-1122 |
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