Helicobacter pylori Induces ERK-dependent Formation of a Phospho-c-Fos·c-Jun Activator Protein-1 Complex That Causes Apoptosis in Macrophages

Macrophages are essential components of innate immunity, and apoptosis of these cells impairs mucosal defense to microbes. Helicobacter pylori is a gastric pathogen that infects half of the world population and causes peptic ulcer disease and gastric cancer. The host inflammatory response fails to e...

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Autors principals: Asim, Mohammad, Chaturvedi, Rupesh, Hoge, Svea, Lewis, Nuruddeen D., Singh, Kshipra, Barry, Daniel P., Algood, Holly S., de Sablet, Thibaut, Gobert, Alain P., Wilson, Keith T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888446/
https://ncbi.nlm.nih.gov/pubmed/20410304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.116988
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