Kinetic and Structural Insights into the Mechanism of AMPylation by VopS Fic Domain

The bacterial pathogen Vibrio parahemeolyticus manipulates host signaling pathways during infections by injecting type III effectors into the cytoplasm of the target cell. One of these effectors, VopS, blocks actin assembly by AMPylation of a conserved threonine residue in the switch 1 region of Rho...

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Bibliografiske detaljer
Main Authors: Luong, Phi, Kinch, Lisa N., Brautigam, Chad A., Grishin, Nick V., Tomchick, Diana R., Orth, Kim
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Enzymology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888428/
https://ncbi.nlm.nih.gov/pubmed/20410310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.114884
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