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Fido, a Novel AMPylation Domain Common to Fic, Doc, and AvrB

BACKGROUND: The Vibrio parahaemolyticus type III secreted effector VopS contains a fic domain that covalently modifies Rho GTPase threonine with AMP to inhibit downstream signaling events in host cells. The VopS fic domain includes a conserved sequence motif (HPFx[D/E]GN[G/K]R) that contributes to A...

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Detalhes bibliográficos
Main Authors: Kinch, Lisa N., Yarbrough, Melanie L., Orth, Kim, Grishin, Nick V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686095/
https://ncbi.nlm.nih.gov/pubmed/19503829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005818
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