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Kinetic and Structural Insights into the Mechanism of AMPylation by VopS Fic Domain
The bacterial pathogen Vibrio parahemeolyticus manipulates host signaling pathways during infections by injecting type III effectors into the cytoplasm of the target cell. One of these effectors, VopS, blocks actin assembly by AMPylation of a conserved threonine residue in the switch 1 region of Rho...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2888428/ https://ncbi.nlm.nih.gov/pubmed/20410310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.114884 |
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