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Kinetic and Structural Insights into the Mechanism of AMPylation by VopS Fic Domain
The bacterial pathogen Vibrio parahemeolyticus manipulates host signaling pathways during infections by injecting type III effectors into the cytoplasm of the target cell. One of these effectors, VopS, blocks actin assembly by AMPylation of a conserved threonine residue in the switch 1 region of Rho...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2888428/ https://ncbi.nlm.nih.gov/pubmed/20410310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.114884 |
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