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Nodal Signaling Regulates the Bone Morphogenic Protein Pluripotency Pathway in Mouse Embryonic Stem Cells

Members of the transforming growth factor-β superfamily play essential roles in both the pluripotency and differentiation of embryonic stem (ES) cells. Although bone morphogenic proteins (BMPs) maintain pluripotency of undifferentiated mouse ES cells, the role of autocrine Nodal signaling is less cl...

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Detalles Bibliográficos
Main Authors: Galvin, Katherine E., Travis, Emily D., Yee, Della, Magnuson, Terry, Vivian, Jay L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888385/
https://ncbi.nlm.nih.gov/pubmed/20427282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.077347
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