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Low oxygen levels induce the expression of the embryonic morphogen Nodal

Low oxygen (O(2)) levels characterize the microenvironment of both stem cells and rapidly growing tumors. Moreover, hypoxia is associated with the maintenance of stem cell–like phenotypes and increased invasion, angiogenesis and metastasis in cancer patients. Metastatic cancers, such as breast cance...

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Detalhes bibliográficos
Main Authors: Quail, Daniela F., Taylor, Meghan J., Walsh, Logan A., Dieters-Castator, Dylan, Das, Padmalaya, Jewer, Michael, Zhang, Guihua, Postovit, Lynne-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237624/
https://ncbi.nlm.nih.gov/pubmed/22031289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-03-0263
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