REGULATION OF FMN SUBDOMAIN INTERACTIONS AND FUNCTION IN NEURONAL NITRIC OXIDE SYNTHASE

Nitric oxide synthases (NOS) are modular, calmodulin (CaM)-dependent, flavo-heme enzymes that catalyze oxidation of L-arginine to generate nitric oxide (NO) and citrulline. During catalysis, the FMN subdomain cycles between interaction with an NADPH-FAD subdomain to receive electrons, and interactio...

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Detalhes bibliográficos
Main Authors: Ilagan, Robielyn P., Tejero, Jesús, Aulak, Kulwant S., Sinha Ray, Sougata, Hemann, Craig, Wang, Zhi-Qiang, Gangoda, Mahinda, Zweier, Jay L., Stuehr, Dennis J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888274/
https://ncbi.nlm.nih.gov/pubmed/19290671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8021087
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