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Analysis of the interactions between the C-terminal cytoplasmic domains of KCNQ1 and KCNE1 channel subunits

Ion channel subunits encoded by KCNQ1 and KCNE1 produce the slowly activating K(+) current (I(Ks)) that plays a central role in myocardial repolarization. The KCNQ1α-subunit and the KCNE1 β-subunit assemble with their membrane-spanning segments interacting resulting in transformation of channel acti...

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Detalhes bibliográficos
Main Authors: Zheng, Renjian, Thompson, Keith, Obeng-Gyimah, Edmond, Alessi, Dana, Chen, Jerri, Cheng, Huiyong, McDonald, Thomas V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888147/
https://ncbi.nlm.nih.gov/pubmed/20196769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20090977
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