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Functional Interactions between KCNE1 C-Terminus and the KCNQ1 Channel

The KCNE1 gene product (minK protein) associates with the cardiac KvLQT1 potassium channel (encoded by KCNQ1) to create the cardiac slowly activating delayed rectifier, I(Ks). Mutations throughout both genes are linked to the hereditary cardiac arrhythmias in the Long QT Syndrome (LQTS). KCNE1 exert...

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Bibliografiske detaljer
Main Authors: Chen, Jerri, Zheng, Renjian, Melman, Yonathan F., McDonald, Thomas V.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659744/
https://ncbi.nlm.nih.gov/pubmed/19340287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005143
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