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Physical and functional interaction sites in cytoplasmic domains of KCNQ1 and KCNE1 channel subunits
The cardiac potassium I(Ks) current is carried by a channel complex formed from α-subunits encoded by KCNQ1 and β-subunits encoded by KCNE1. Deleterious mutations in either gene are associated with hereditary long QT syndrome. Interactions between the transmembrane domains of the α- and β-subunits d...
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| Publicado no: | Am J Physiol Heart Circ Physiol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7052629/ https://ncbi.nlm.nih.gov/pubmed/31834838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00459.2019 |
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