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A Concise, Phosphate-Mediated Approach to the Total Synthesis of (−)-Tetrahydrolipstatin

[Image: see text] An efficient synthesis of (−)-tetrahydrolipstatin (THL) is reported. This method takes advantage of a phosphate tether-mediated, one-pot, sequential RCM/CM/hydrogenation protocol to deliver THL in 8 total steps from a readily prepared (S,S)-triene. The strategy incorporates selecti...

詳細記述

保存先:
書誌詳細
主要な著者: Venukadasula, Phanindra K. M., Chegondi, Rambabu, Maitra, Soma, Hanson, Paul R.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888003/
https://ncbi.nlm.nih.gov/pubmed/20196547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol1002913
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