pARIS-htt: an optimised expression platform to study huntingtin reveals functional domains required for vesicular trafficking

BACKGROUND: Huntingtin (htt) is a multi-domain protein of 350 kDa that is mutated in Huntington's disease (HD) but whose function is yet to be fully understood. This absence of information is due in part to the difficulty of manipulating large DNA fragments by using conventional molecular cloni...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Pardo, Raúl, Molina-Calavita, Maria, Poizat, Ghislaine, Keryer, Guy, Humbert, Sandrine, Saudou, Frédéric
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2010
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887845/
https://ncbi.nlm.nih.gov/pubmed/20515468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-3-17
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы