pARIS-htt: an optimised expression platform to study huntingtin reveals functional domains required for vesicular trafficking

BACKGROUND: Huntingtin (htt) is a multi-domain protein of 350 kDa that is mutated in Huntington's disease (HD) but whose function is yet to be fully understood. This absence of information is due in part to the difficulty of manipulating large DNA fragments by using conventional molecular cloni...

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Detalhes bibliográficos
Main Authors: Pardo, Raúl, Molina-Calavita, Maria, Poizat, Ghislaine, Keryer, Guy, Humbert, Sandrine, Saudou, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887845/
https://ncbi.nlm.nih.gov/pubmed/20515468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-3-17
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