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OPRM1 SNP (A118G): Involvement in disease development, treatment response, and animal models

Endogenous opioids acting at μ-opioid receptors mediate many biological functions. Pharmacological intervention at these receptors has greatly aided in the treatment of acute and chronic pain, in addition to other uses. However, the development of tolerance and dependence has made it difficult to ad...

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Detalhes bibliográficos
Main Authors: Mague, Stephen D., Blendy, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887703/
https://ncbi.nlm.nih.gov/pubmed/20074870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2009.12.016
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