Metal ion roles and the movement of hydrogen during the reaction catalyzed by d-xylose isomerase: a joint X-ray and neutron diffraction study

Conversion of aldo to keto sugars by the metalloenzyme d-xylose isomerase (XI) is a multi-step reaction involving hydrogen transfer. We have determined the structure of this enzyme by neutron diffraction in order to locate H atoms (or their isotope D). Two studies are presented, one of XI containing...

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Main Authors: Kovalevsky, Andrey Y., Hanson, Leif, Fisher, S. Zoe, Mustyakimov, Marat, Mason, Sax, Forsyth, Trevor, Blakeley, Matthew P., Kean, David. A., Wagner, Trixie, Carrell, H. L., Katz, Amy K., Glusker, Jenny P., Langan, Paul
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887347/
https://ncbi.nlm.nih.gov/pubmed/20541506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.03.011
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