Locating active-site hydrogen atoms in d-xylose isomerase: Time-of-flight neutron diffraction

Time-of-flight neutron diffraction has been used to locate hydrogen atoms that define the ionization states of amino acids in crystals of d-xylose isomerase. This enzyme, from Streptomyces rubiginosus, is one of the largest enzymes studied to date at high resolution (1.8 Å) by this method. We have d...

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Autori principali: Katz, Amy K., Li, Xinmin, Carrell, H. L., Hanson, B. Leif, Langan, Paul, Coates, Leighton, Schoenborn, Benno P., Glusker, Jenny P., Bunick, Gerard J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482496/
https://ncbi.nlm.nih.gov/pubmed/16707576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602598103
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