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Helix unwinding and base flipping enable human MTERF1 to terminate mitochondrial transcription
Defects in mitochondrial gene expression are associated with aging and disease. Mterf proteins have been implicated in modulating transcription, replication and protein synthesis. We have solved the structure of a member of this family, the human mitochondrial transcriptional terminator MTERF1, boun...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2887341/ https://ncbi.nlm.nih.gov/pubmed/20550934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.05.018 |
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