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Base flipping by MTERF1 can accommodate multiple conformations and occurs in a stepwise fashion
Human mitochondrial transcription termination occurs within the leu-tRNA gene and is mediated by the DNA binding protein MTERF1. The crystal structure of MTERF1 bound to the canonical termination sequence reveals a rare base flipping event that involves the eversion of three nucleotides. These nucle...
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| Publicado no: | J Mol Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4851923/ https://ncbi.nlm.nih.gov/pubmed/26523681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.10.021 |
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