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Structure of the essential MTERF4:NSUN4 protein complex reveals how an MTERF protein collaborates to facilitate rRNA modification

MTERF4 is the first MTERF family member shown to bind RNA, and plays an essential role as a regulator of ribosomal biogenesis in mammalian mitochondria. It forms a complex with the rRNA methyltransferase NSUN4 and recruits it to the large ribosomal subunit. In this paper, we characterize the interac...

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Main Authors: Yakubovskaya, Elena, Guja, Kip E., Mejia, Edison, Castano, Steven, Hambardjieva, Elena, Choi, Woo Suk, Garcia-Diaz, Miguel
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496059/
https://ncbi.nlm.nih.gov/pubmed/23022348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.08.027
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