Structural basis for S-adenosylmethionine binding and methyltransferase activity by mitochondrial transcription factor B1

Eukaryotic transcription factor B (TFB) proteins are homologous to KsgA/Dim1 ribosomal RNA (rRNA) methyltransferases. The mammalian TFB1, mitochondrial (TFB1M) factor is an essential protein necessary for mitochondrial gene expression. TFB1M mediates an rRNA modification in the small ribosomal subun...

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Bibliographische Detailangaben
Hauptverfasser: Guja, Kip E., Venkataraman, Krithika, Yakubovskaya, Elena, Shi, Hui, Mejia, Edison, Hambardjieva, Elena, Karzai, A. Wali, Garcia-Diaz, Miguel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
Structural Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763538/
https://ncbi.nlm.nih.gov/pubmed/23804760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt547
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