Forward operation of adenine nucleotide translocase during F(0)F(1)-ATPase reversal: critical role of matrix substrate-level phosphorylation

In pathological conditions, F(0)F(1)-ATPase hydrolyzes ATP in an attempt to maintain mitochondrial membrane potential. Using thermodynamic assumptions and computer modeling, we established that mitochondrial membrane potential can be more negative than the reversal potential of the adenine nucleotid...

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Main Authors: Chinopoulos, Christos, Gerencser, Akos A., Mandi, Miklos, Mathe, Katalin, Töröcsik, Beata, Doczi, Judit, Turiak, Lilla, Kiss, Gergely, Konràd, Csaba, Vajda, Szilvia, Vereczki, Viktoria, Oh, Richard J., Adam-Vizi, Vera
Format: Artigo
Jezik:Inglês
Izdano: The Federation of American Societies for Experimental Biology 2010
Teme:
Research Communications
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887268/
https://ncbi.nlm.nih.gov/pubmed/20207940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-149898
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