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Modulation of F(0)F(1)-ATP synthase activity by cyclophilin D regulates matrix adenine nucleotide levels

Cyclophilin D was recently shown to bind to and decrease the activity of F(0)F(1)-ATP synthase in submitochondrial particles and permeabilized mitochondria (Giorgio et al. 2009, J Biol Chem, 284:33982). Cyclophilin D binding decreased both the ATP synthesis and hydrolysis rates. Here, we reaffirm th...

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Detalhes bibliográficos
Main Authors: Chinopoulos, Christos, Konràd, Csaba, Kiss, Gergely, Metelkin, Eugeniy, Töröcsik, Beata, Zhang, Steven F., Starkov, Anatoly A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062657/
https://ncbi.nlm.nih.gov/pubmed/21281446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2011.08026.x
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